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Suppression of experimental uveitis by a recombinant adeno-associated virus vector encoding interleukin-1 receptor antagonist

PURPOSE: To evaluate the potential of gene therapy with a recombinant adeno-associated virus vector encoding the interleukin-1 receptor antagonist gene (rAAV-IL-1Ra) in the treatment of experimental uveitis. METHODS: The vitreal cavity of New Zealand white rabbits was injected with rAAV-IL-1Ra (4×10...

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Detalles Bibliográficos
Autores principales: Tsai, Ming-Ling, Horng, Chi-Ting, Chen, Show-Li, Xiao, Xiao, Wang, Chih-Hung, Tsao, Yeou-Ping
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723168/
https://www.ncbi.nlm.nih.gov/pubmed/19693263