Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys

The holy grail for HIV vaccine development is an immunogen that elicits persisting antibodies with broad neutralizing activity against field strains of the virus. Unfortunately, very little progress has been made in finding or designing such immunogens. Using the SIV model, we have taken a markedly...

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Detalles Bibliográficos
Autores principales: Johnson, Philip R, Schnepp, Bruce C, Zhang, Jianchao, Connell, Mary J, Greene, Sean M, Yuste, Eloisa, Desrosiers, Ronald C, Clark, K Reed
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723177/
https://www.ncbi.nlm.nih.gov/pubmed/19448633
http://dx.doi.org/10.1038/nm.1967

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