Cargando…

A Core MYC Gene Expression Signature Is Prominent in Basal-Like Breast Cancer but Only Partially Overlaps the Core Serum Response

BACKGROUND: The MYC oncogene contributes to induction and growth of many cancers but the full spectrum of the MYC transcriptional response remains unclear. METHODOLOGY/PRINCIPAL FINDINGS: Using microarrays, we conducted a detailed kinetic study of genes that respond to MYCN or MYCNΔMBII induction in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chandriani, Sanjay, Frengen, Eirik, Cowling, Victoria H., Pendergrass, Sarah A., Perou, Charles M., Whitfield, Michael L., Cole, Michael D.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723908/ https://www.ncbi.nlm.nih.gov/pubmed/19690609 http://dx.doi.org/10.1371/journal.pone.0006693

Ejemplares similares

Core species and interactions prominent in fish-associated microbiome dynamics
por: Yajima, Daii, et al.
Publicado: (2023)

The Unique Value of Core-only Continuing Medical Education
por: Lupo, Mary P., et al.
Publicado: (2016)

Selective Activation of Alternative MYC Core Promoters by Wnt-Responsive Enhancers
por: Bardales, Jorge A., et al.
Publicado: (2018)

Two independent transcription initiation codes overlap on vertebrate core promoters
por: Haberle, Vanja, et al.
Publicado: (2014)

Human Adult Fibroblast‐like Synoviocytes and Articular Chondrocytes Exhibit Prominent Overlap in Their Transcriptomic Signatures
por: Jones, Kyle, et al.
Publicado: (2021)

A multivariable approach for risk markers from pooled molecular data with only partial overlap
por: Stelzer, Anne-Sophie, et al.
Publicado: (2019)

Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors
por: Cole, Michael D., et al.
Publicado: (2009)

Mutations in pre-core and basal-core promoter regions of hepatitis B virus in chronic HBV patients from Golestan, Iran
por: Moradi, Abdolvahab, et al.
Publicado: (2014)

MYC-related microRNAs signatures in non-Hodgkin B-cell lymphomas and their relationships with core cellular pathways
por: Malpeli, Giorgio, et al.
Publicado: (2018)

Predicting overlapping protein complexes based on core-attachment and a local modularity structure
por: Wang, Rongquan, et al.
Publicado: (2018)

The Nematic Phases of Bent-Core Liquid Crystals
por: Gleeson, Helen F, et al.
Publicado: (2014)

Host Transcript Accumulation during Lytic KSHV Infection Reveals Several Classes of Host Responses
por: Chandriani, Sanjay, et al.
Publicado: (2007)

Toward Human Rights-Consistent Responses to Health Emergencies: What Is the Overlap between Core Right to Health Obligations and Core International Health Regulation Capacities?
por: Toebes, Brigit, et al.
Publicado: (2020)

Stable Electrospinning of Core-Functionalized Coaxial Fibers Enabled by the Minimum-Energy Interface Given by Partial Core–Sheath Miscibility
por: Vats, Shameek, et al.
Publicado: (2021)

Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cells
por: Albert, Thomas K, et al.
Publicado: (2010)

A new basal promoter element recognized by RNA polymerase core enzyme
por: Yuzenkova, Yulia, et al.
Publicado: (2011)

The Importance of Hepatitis B Virus Genome Diversity in Basal Core Promoter Region
por: Mohamadkhani, A, et al.
Publicado: (2011)

Evolutionary relationships and taxonomy of Microtea (Microteaceae), a basal lineage in the core Caryophyllales
por: Sukhorukov, Alexander P., et al.
Publicado: (2019)

Bioinformatic analysis suggests that the Cypovirus 1 major core protein cistron harbours an overlapping gene
por: Firth, Andrew E, et al.
Publicado: (2008)

A partially equilibrated initial mantle and core indicated by stress-induced percolative core formation through a bridgmanite matrix
por: Wang, Lin, et al.
Publicado: (2023)

Hypoxia inducible factors regulate hepatitis B virus replication by activating the basal core promoter
por: Wing, Peter A.C., et al.
Publicado: (2021)

Degeneration of basal and limbic networks is a core feature of behavioural variant frontotemporal dementia
por: Vuksanović, Vesna, et al.
Publicado: (2021)

Investigation of DNA Sequence in the Basal Core Promoter, Precore, and Core Regions of Hepatitis B Virus from Tunisia Shows a Shift in Genotype Prevalence
por: Ayari, Rym, et al.
Publicado: (2012)

Myc and mRNA capping()
por: Dunn, Sianadh, et al.
Publicado: (2015)

Myc and Max Genome-Wide Binding Sites Analysis Links the Myc Regulatory Network with the Polycomb and the Core Pluripotency Networks in Mouse Embryonic Stem Cells
por: Krepelova, Anna, et al.
Publicado: (2014)

Winter behavior of Saimaa ringed seals: Non-overlapping core areas as indicators of avoidance in breeding females
por: Niemi, Marja, et al.
Publicado: (2019)

Comparison of MHG and DZsig reveals shared biology and a core overlap group with inferior prognosis in DLBCL
por: Davies, John R., et al.
Publicado: (2023)

An analysis of research biopsy core variability from over 5000 prospectively collected core samples
por: Bhamidipati, Deepak, et al.
Publicado: (2021)

Associations between hepatitis B virus basal core promoter/pre-core region mutations and the risk of acute-on-chronic liver failure: a meta-analysis
por: Hu, Feishu, et al.
Publicado: (2015)

Epidemics in Partially Overlapped Multiplex Networks
por: Buono, Camila, et al.
Publicado: (2014)

Burkitt’s lymphoma-associated c-Myc mutations converge on a dramatically altered target gene response and implicate Nol5a/Nop56 in oncogenesis
por: Cowling, Victoria H., et al.
Publicado: (2013)

Effects of core strength training on core stability
por: Hsu, Shih-Lin, et al.
Publicado: (2018)

Mutations of Basal Core Promoter and Precore Regions in Hepatitis B Virus Genotypes B and C
por: Huang, Yong, et al.
Publicado: (2014)

Competency and the Six Core Competencies
por: Kavic, Michael S.
Publicado: (2002)

Identification of drug targets for the treatment of Basal-like tumors
por: Hoadley, KA, et al.
Publicado: (2005)

Prominent Longitudinal Strain Reduction of Basal Left Ventricular Segments in Patients With Coronavirus Disease-19
por: Goerlich, Erin, et al.
Publicado: (2021)

A lobulated mass on the upper back with prominent vasculature: A giant basal cell carcinoma
por: Kolitz, Elysha M., et al.
Publicado: (2021)

Metaplastic breast carcinoma producing prominent basal lamina with neuroendocrine differentiation: A case report
por: Furuya, Yoshitaka, et al.
Publicado: (2023)

A Novel Cis-Acting RNA Structural Element Embedded in the Core Coding Region of the Hepatitis C Virus Genome Directs Internal Translation Initiation of the Overlapping Core+1 ORF
por: Vassilaki, Niki, et al.
Publicado: (2020)

Constrained evolution of overlapping genes in viral host adaptation: Acquisition of glycosylation motifs in hepadnaviral precore/core genes
por: Hong, Xupeng, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6beqmccnc628jmmokls2eim5rk