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HLA-Associated Immune Escape Pathways in HIV-1 Subtype B Gag, Pol and Nef Proteins
BACKGROUND: Despite the extensive genetic diversity of HIV-1, viral evolution in response to immune selective pressures follows broadly predictable mutational patterns. Sites and pathways of Human Leukocyte-Antigen (HLA)-associated polymorphisms in HIV-1 have been identified through the analysis of...
Autores principales: | Brumme, Zabrina L., John, Mina, Carlson, Jonathan M., Brumme, Chanson J., Chan, Dennison, Brockman, Mark A., Swenson, Luke C., Tao, Iris, Szeto, Sharon, Rosato, Pamela, Sela, Jennifer, Kadie, Carl M., Frahm, Nicole, Brander, Christian, Haas, David W., Riddler, Sharon A., Haubrich, Richard, Walker, Bruce D., Harrigan, P. Richard, Heckerman, David, Mallal, Simon |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723923/ https://www.ncbi.nlm.nih.gov/pubmed/19690614 http://dx.doi.org/10.1371/journal.pone.0006687 |
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