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Crystal Structure of Escherichia coli Polynucleotide Phosphorylase Core Bound to RNase E, RNA and Manganese: Implications for Catalytic Mechanism and RNA Degradosome Assembly
Polynucleotide phosphorylase (PNPase) is a processive exoribonuclease that contributes to messenger RNA turnover and quality control of ribosomal RNA precursors in many bacterial species. In Escherichia coli, a proportion of the PNPase is recruited into a multi-enzyme assembly, known as the RNA degr...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Elsevier
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2723993/ https://www.ncbi.nlm.nih.gov/pubmed/19327365 http://dx.doi.org/10.1016/j.jmb.2009.03.051 |