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Topology is the Principal Determinant in the Folding of a Complex All-alpha Greek Key Death Domain from Human FADD
In order to elucidate the relative importance of secondary structure and topology in determining folding mechanism, we have carried out a phi-value analysis of the death domain (DD) from human FADD. FADD DD is a 100 amino acid domain consisting of six anti-parallel alpha helices arranged in a Greek...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724026/ https://www.ncbi.nlm.nih.gov/pubmed/19362094 http://dx.doi.org/10.1016/j.jmb.2009.04.004 |