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The Structure of OMCI, a Novel Lipocalin Inhibitor of the Complement System
The complement (C) system is a potent innate immune defence system against parasites. We have recently characterised and expressed OmCI, a 16 kDa protein derived from the soft tick Ornithodoros moubata that specifically binds C5, thereby preventing C activation. The structure of recombinant OmCI det...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2007
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724154/ https://www.ncbi.nlm.nih.gov/pubmed/17445829 http://dx.doi.org/10.1016/j.jmb.2007.03.064 |