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A physical and functional link between splicing factors promotes pre-mRNA 3′ end processing

Polypyrimidine tract-binding protein (PTB) is a splicing regulator that also plays a positive role in pre-mRNA 3′ end processing when bound upstream of the polyadenylation signal (pA signal). Here, we address the mechanism of PTB stimulatory function in mRNA 3′ end formation. We identify PTB as the...

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Detalles Bibliográficos
Autores principales:	Millevoi, Stefania, Decorsière, Adrien, Loulergue, Clarisse, Iacovoni, Jason, Bernat, Sandra, Antoniou, Michael, Vagner, Stéphan
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724285/ https://www.ncbi.nlm.nih.gov/pubmed/19506027 http://dx.doi.org/10.1093/nar/gkp470

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