Studying vertebrate topoisomerase 2 function using a conditional knockdown system in DT40 cells

DT40 is a B-cell lymphoma-derived avian cell line widely used to study cell autonomous gene function because of the high rates with which DNA constructs are homologously recombined into its genome. Here, we demonstrate that the power of the DT40 system can be extended yet further through the use of...

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Detalles Bibliográficos
Autores principales: Johnson, Mark, Phua, Hui Hui, Bennett, Sophia C., Spence, Jennifer M., Farr, Christine J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724289/
https://www.ncbi.nlm.nih.gov/pubmed/19494182
http://dx.doi.org/10.1093/nar/gkp480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724289/
https://www.ncbi.nlm.nih.gov/pubmed/19494182
http://dx.doi.org/10.1093/nar/gkp480

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