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Studying vertebrate topoisomerase 2 function using a conditional knockdown system in DT40 cells
DT40 is a B-cell lymphoma-derived avian cell line widely used to study cell autonomous gene function because of the high rates with which DNA constructs are homologously recombined into its genome. Here, we demonstrate that the power of the DT40 system can be extended yet further through the use of...
Autores principales: | Johnson, Mark, Phua, Hui Hui, Bennett, Sophia C., Spence, Jennifer M., Farr, Christine J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724289/ https://www.ncbi.nlm.nih.gov/pubmed/19494182 http://dx.doi.org/10.1093/nar/gkp480 |
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