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Multiple histone modifications in euchromatin promote heterochromatin formation by redundant mechanisms in Saccharomyces cerevisiae

BACKGROUND: Methylation of lysine 79 on histone H3 by Dot1 is required for maintenance of heterochromatin structure in yeast and humans. However, this histone modification occurs predominantly in euchromatin. Thus, Dot1 affects silencing by indirect mechanisms and does not act by the recruitment mod...

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Detalles Bibliográficos
Autores principales:	Verzijlbergen, Kitty F, Faber, Alex W, Stulemeijer, Iris JE, van Leeuwen, Fred
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724485/ https://www.ncbi.nlm.nih.gov/pubmed/19638198 http://dx.doi.org/10.1186/1471-2199-10-76

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