Cargando…
Targeting the Progression of Parkinson’s Disease
By the time a patient first presents with symptoms of Parkinson’s disease at the clinic, a significant proportion (50-70%) of the cells in the substantia nigra (SN) has already been destroyed. This degeneration progresses until, within a few years, most of the cells have died. Except for rare cases...
Autores principales: | George, J.L, Mok, S, Moses, D, Wilkins, S, Bush, A.I, Cherny, R.A, Finkelstein, D.I |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers Ltd.
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724666/ https://www.ncbi.nlm.nih.gov/pubmed/19721815 http://dx.doi.org/10.2174/157015909787602814 |
Ejemplares similares
-
Iron accumulation confers neurotoxicity to a vulnerable population of nigral neurons: implications for Parkinson’s disease
por: Ayton, Scott, et al.
Publicado: (2014) -
The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson’s disease
por: Finkelstein, David I., et al.
Publicado: (2017) -
Correction to: The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson’s disease
por: Finkelstein, David I., et al.
Publicado: (2021) -
Transferrin protects against Parkinsonian neurotoxicity and is deficient in Parkinson’s substantia nigra
por: Ayton, Scott, et al.
Publicado: (2016) -
Mechanisms of Copper Ion Mediated Huntington's Disease Progression
por: Fox, Jonathan H., et al.
Publicado: (2007)