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Glia and Muscle Sculpt Neuromuscular Arbors by Engulfing Destabilized Synaptic Boutons and Shed Presynaptic Debris

Synapse remodeling is an extremely dynamic process, often regulated by neural activity. Here we show during activity-dependent synaptic growth at the Drosophila NMJ many immature synaptic boutons fail to form stable postsynaptic contacts, are selectively shed from the parent arbor, and degenerate or...

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Detalles Bibliográficos
Autores principales: Fuentes-Medel, Yuly, Logan, Mary A., Ashley, James, Ataman, Bulent, Budnik, Vivian, Freeman, Marc R.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724735/
https://www.ncbi.nlm.nih.gov/pubmed/19707574
http://dx.doi.org/10.1371/journal.pbio.1000184