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Exon 6 of human JAG1 encodes a conserved structural unit
BACKGROUND: Notch signaling drives developmental processes in all metazoans. The receptor binding region of the human Notch ligand Jagged-1 is made of a DSL (Delta/Serrate/Lag-2) domain and two atypical epidermal growth factor (EGF) repeats encoded by two exons, exon 5 and 6, which are out of phase...
Autores principales: | Pintar, Alessandro, Guarnaccia, Corrado, Dhir, Somdutta, Pongor, Sándor |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725086/ https://www.ncbi.nlm.nih.gov/pubmed/19586525 http://dx.doi.org/10.1186/1472-6807-9-43 |
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