Cargando…
Risk of suicidality in clinical trials of antidepressants in adults: analysis of proprietary data submitted to US Food and Drug Administration
Objective To examine the risk of suicidal behaviour within clinical trials of antidepressants in adults. Design Meta-analysis of 372 double blind randomised placebo controlled trials. Setting Drug development programmes for any indication in adults. Participants 99 231 adults assigned to antidepress...
Autores principales: | Stone, Marc, Laughren, Thomas, Jones, M Lisa, Levenson, Mark, Holland, P Chris, Hughes, Alice, Hammad, Tarek A, Temple, Robert, Rochester, George |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group Ltd.
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725270/ https://www.ncbi.nlm.nih.gov/pubmed/19671933 http://dx.doi.org/10.1136/bmj.b2880 |
Ejemplares similares
-
Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration
por: Kirsch, Irving, et al.
Publicado: (2008) -
Regarding Combined Pediatric and Adult Trials Submitted to the US Food and Drug Administration 2012–2018
por: Cook, Jack, et al.
Publicado: (2020) -
Proprietaries
Publicado: (1904) -
Use of Quantile Treatment Effects Analysis to Describe Antidepressant Response in Randomized Clinical Trials Submitted to the US Food and Drug Administration: A Secondary Analysis of Pooled Trial Data
por: Meyerson, William U., et al.
Publicado: (2023) -
Increases in Suicide Deaths Among Adolescents and Young Adults Following US Food and Drug Administration Antidepressant Boxed Warnings and Declines in Depression Care
por: Lu, Christine Y., et al.
Publicado: (2020)