Cargando…
Impact of Chromatin Structures on DNA Processing for Genomic Analyses
Chromatin has an impact on recombination, repair, replication, and evolution of DNA. Here we report that chromatin structure also affects laboratory DNA manipulation in ways that distort the results of chromatin immunoprecipitation (ChIP) experiments. We initially discovered this effect at the Sacch...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725323/ https://www.ncbi.nlm.nih.gov/pubmed/19693276 http://dx.doi.org/10.1371/journal.pone.0006700 |