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Rapidly Fatal Acanthamoeba Encephalitis and Treatment of Cryoglobulinemia

We describe a 66-year-old woman with therapy-refractory cryoglobulinemia treated with rituximab, plasmapheresis, and steroids; a case of fatal meningoencephalitis caused by Acanthamoeba spp. then developed. Such infections are rare and show an unusually rapid course (possibly related to rituximab).

Detalles Bibliográficos
Autores principales: Meersseman, Wouter, Lagrou, Katrien, Sciot, Raf, de Jonckheere, Johan, Haberler, Christine, Walochnik, Julia, Peetermans, Willy E., van Wijngaerden, Eric
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725922/
https://www.ncbi.nlm.nih.gov/pubmed/17552103
http://dx.doi.org/10.3201/eid1303.061001
Descripción
Sumario:We describe a 66-year-old woman with therapy-refractory cryoglobulinemia treated with rituximab, plasmapheresis, and steroids; a case of fatal meningoencephalitis caused by Acanthamoeba spp. then developed. Such infections are rare and show an unusually rapid course (possibly related to rituximab).