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Genetic Stasis of Dominant West Nile Virus Genotype, Houston, Texas

The accumulation and fixation of mutations in West Nile virus (WNV) led to the emergence of a dominant genotype throughout North America. Subsequent analysis of 44 isolates, including 19 new sequences, from Houston, Texas, suggests that WNV has reached relative genetic stasis at the local level in r...

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Detalles Bibliográficos
Autores principales: Davis, C. Todd, Li, Li, May, Fiona J., Bueno, Rudy, Dennett, James A., Bala, Adil A., Guzman, Hilda, Elizondo-Quiroga, Darwin, Tesh, Robert B., Barrett, Alan D.
Formato: Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2725985/
https://www.ncbi.nlm.nih.gov/pubmed/17553276
http://dx.doi.org/10.3201/eid1304.061473
Descripción
Sumario:The accumulation and fixation of mutations in West Nile virus (WNV) led to the emergence of a dominant genotype throughout North America. Subsequent analysis of 44 isolates, including 19 new sequences, from Houston, Texas, suggests that WNV has reached relative genetic stasis at the local level in recent years.