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A Dictyostelium chalone uses G proteins to regulate proliferation

BACKGROUND: Several studies have shown that organ size, and the proliferation of tumor metastases, may be regulated by negative feedback loops in which autocrine secreted factors called chalones inhibit proliferation. However, very little is known about chalones, and how cells sense them. We previou...

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Detalles Bibliográficos
Autores principales: Bakthavatsalam, Deenadayalan, Choe, Jonathan M, Hanson, Nana E, Gomer, Richard H
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726123/
https://www.ncbi.nlm.nih.gov/pubmed/19635129
http://dx.doi.org/10.1186/1741-7007-7-44