Constitutive RB1 mutation in a child conceived by in vitro fertilization: implications for genetic counseling

BACKGROUND: The purpose of this study was to identify mutations associated with bilateral retinoblastoma in a quadruplet conceived by in vitro fertilization, and to trace the parental origin of mutations in the four quadruplets and their father. METHODS: Mutational screening was carried out by seque...

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Detalles Bibliográficos
Autores principales: Barbosa, Raquel H, Vargas, Fernando R, Lucena, Evandro, Bonvicino, Cibele R, Seuánez, Héctor N
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726130/
https://www.ncbi.nlm.nih.gov/pubmed/19640284
http://dx.doi.org/10.1186/1471-2350-10-75

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