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Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide

BACKGROUND: The abnormal accumulation of amyloid-beta peptide is believed to cause malfunctioning of neurons in the Alzheimer's disease brain. Amyloid-beta exists in different assembly forms in the aging mammalian brain including monomers, oligomers, and aggregates, and in senile plaques, fibri...

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Detalles Bibliográficos
Autores principales: Yamin, Rina, Zhao, Cheng, O'Connor, Peter B, McKee, Ann C, Abraham, Carmela R
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726140/
https://www.ncbi.nlm.nih.gov/pubmed/19627603
http://dx.doi.org/10.1186/1750-1326-4-33