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Acyl peptide hydrolase degrades monomeric and oligomeric amyloid-beta peptide
BACKGROUND: The abnormal accumulation of amyloid-beta peptide is believed to cause malfunctioning of neurons in the Alzheimer's disease brain. Amyloid-beta exists in different assembly forms in the aging mammalian brain including monomers, oligomers, and aggregates, and in senile plaques, fibri...
Autores principales: | Yamin, Rina, Zhao, Cheng, O'Connor, Peter B, McKee, Ann C, Abraham, Carmela R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726140/ https://www.ncbi.nlm.nih.gov/pubmed/19627603 http://dx.doi.org/10.1186/1750-1326-4-33 |
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