Electron Crystallography Reveals Plasticity within the Drug Binding Site of the Small Multidrug Transporter EmrE

EmrE is a Small Multidrug Resistance transporter (SMR) family member that mediates counter transport of protons and hydrophobic cationic drugs such as tetraphenylphosphonium (TPP(+)), ethidium, propidium and dequalinium. It is thought that the selectivity of the drug binding site in EmrE is defined...

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Detalles Bibliográficos
Autores principales: Korkhov, Vladimir M., Tate, Christopher G.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726284/
https://www.ncbi.nlm.nih.gov/pubmed/18295794
http://dx.doi.org/10.1016/j.jmb.2008.01.056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726284/
https://www.ncbi.nlm.nih.gov/pubmed/18295794
http://dx.doi.org/10.1016/j.jmb.2008.01.056

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