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Electron Crystallography Reveals Plasticity within the Drug Binding Site of the Small Multidrug Transporter EmrE
EmrE is a Small Multidrug Resistance transporter (SMR) family member that mediates counter transport of protons and hydrophobic cationic drugs such as tetraphenylphosphonium (TPP(+)), ethidium, propidium and dequalinium. It is thought that the selectivity of the drug binding site in EmrE is defined...
Autores principales: | Korkhov, Vladimir M., Tate, Christopher G. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726284/ https://www.ncbi.nlm.nih.gov/pubmed/18295794 http://dx.doi.org/10.1016/j.jmb.2008.01.056 |
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