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Decoding of Methylated Histone H3 Tail by the Pygo-BCL9 Wnt Signaling Complex
Pygo and BCL9/Legless transduce the Wnt signal by promoting the transcriptional activity of β-catenin/Armadillo in normal and malignant cells. We show that human and Drosophila Pygo PHD fingers associate with their cognate HD1 domains from BCL9/Legless to bind specifically to the histone H3 tail met...
Autores principales: | Fiedler, Marc, Sánchez-Barrena, María José, Nekrasov, Maxim, Mieszczanek, Juliusz, Rybin, Vladimir, Müller, Jürg, Evans, Phil, Bienz, Mariann |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726290/ https://www.ncbi.nlm.nih.gov/pubmed/18498752 http://dx.doi.org/10.1016/j.molcel.2008.03.011 |
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