Transgenic CHD1L Expression in Mouse Induces Spontaneous Tumors

BACKGROUND: Amplification of 1q21 is the most frequent genetic alteration in hepatocellular carcinoma (HCC), which was detected in 58–78% of primary HCC cases by comparative genomic hybridization (CGH). Using chromosome microdissection/hybrid selection approach we recently isolated a candidate oncog...

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Detalles Bibliográficos
Autores principales: Chen, Muhan, Huang, Jian-dong, Hu, Liang, Zheng, Bo-jian, Chen, Leilei, Tsang, Sze Lan, Guan, Xin-yuan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726430/
https://www.ncbi.nlm.nih.gov/pubmed/19701453
http://dx.doi.org/10.1371/journal.pone.0006727

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