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Beta-2-transferrin to detect cerebrospinal fluid pleural effusion: a case report
INTRODUCTION: Pleural effusion secondary to ventriculoperitoneal shunt insertion is a rare and potentially life-threatening occurrence. CASE PRESENTATION: We describe a 14-month-old Caucasian boy who had a ventriculoperitoneal shunt inserted for progressive hydrocephalus of unknown etiology. Two and...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726474/ https://www.ncbi.nlm.nih.gov/pubmed/19830108 http://dx.doi.org/10.1186/1752-1947-3-6495 |
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author | Smith, Jennifer C Cohen, Eyal |
author_facet | Smith, Jennifer C Cohen, Eyal |
author_sort | Smith, Jennifer C |
collection | PubMed |
description | INTRODUCTION: Pleural effusion secondary to ventriculoperitoneal shunt insertion is a rare and potentially life-threatening occurrence. CASE PRESENTATION: We describe a 14-month-old Caucasian boy who had a ventriculoperitoneal shunt inserted for progressive hydrocephalus of unknown etiology. Two and a half months post-shunt insertion, the patient presented with mild respiratory distress. A chest radiograph revealed a large right pleural effusion and a shunt series demonstrated an appropriately placed distal catheter tip. A subsequent abdominal ultrasound revealed marked ascites. Fluid drained via tube thoracostomy was sent for beta-2-transferrin electrophoresis. A positive test was highly suggestive of cerebral spinal fluid hydrothorax. Post-externalization of the ventriculoperitoneal shunt, the ascites and pleural effusion resolved. CONCLUSION: Testing for beta-2-transferrin protein in pleural fluid may serve as a useful technique for diagnosing cerebrospinal fluid hydrothorax in patients with ventriculoperitoneal shunts. |
format | Text |
id | pubmed-2726474 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-27264742009-10-14 Beta-2-transferrin to detect cerebrospinal fluid pleural effusion: a case report Smith, Jennifer C Cohen, Eyal J Med Case Reports Case report INTRODUCTION: Pleural effusion secondary to ventriculoperitoneal shunt insertion is a rare and potentially life-threatening occurrence. CASE PRESENTATION: We describe a 14-month-old Caucasian boy who had a ventriculoperitoneal shunt inserted for progressive hydrocephalus of unknown etiology. Two and a half months post-shunt insertion, the patient presented with mild respiratory distress. A chest radiograph revealed a large right pleural effusion and a shunt series demonstrated an appropriately placed distal catheter tip. A subsequent abdominal ultrasound revealed marked ascites. Fluid drained via tube thoracostomy was sent for beta-2-transferrin electrophoresis. A positive test was highly suggestive of cerebral spinal fluid hydrothorax. Post-externalization of the ventriculoperitoneal shunt, the ascites and pleural effusion resolved. CONCLUSION: Testing for beta-2-transferrin protein in pleural fluid may serve as a useful technique for diagnosing cerebrospinal fluid hydrothorax in patients with ventriculoperitoneal shunts. BioMed Central 2009-03-13 /pmc/articles/PMC2726474/ /pubmed/19830108 http://dx.doi.org/10.1186/1752-1947-3-6495 Text en Copyright ©2009 licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case report Smith, Jennifer C Cohen, Eyal Beta-2-transferrin to detect cerebrospinal fluid pleural effusion: a case report |
title | Beta-2-transferrin to detect cerebrospinal fluid pleural effusion: a case report |
title_full | Beta-2-transferrin to detect cerebrospinal fluid pleural effusion: a case report |
title_fullStr | Beta-2-transferrin to detect cerebrospinal fluid pleural effusion: a case report |
title_full_unstemmed | Beta-2-transferrin to detect cerebrospinal fluid pleural effusion: a case report |
title_short | Beta-2-transferrin to detect cerebrospinal fluid pleural effusion: a case report |
title_sort | beta-2-transferrin to detect cerebrospinal fluid pleural effusion: a case report |
topic | Case report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726474/ https://www.ncbi.nlm.nih.gov/pubmed/19830108 http://dx.doi.org/10.1186/1752-1947-3-6495 |
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