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Templated Synthesis of Peptide Nucleic Acids via Sequence-Selective Base-Filling Reactions

[Image: see text] The templated synthesis of nucleic acids has previously been achieved through the backbone ligation of preformed nucleotide monomers or oligomers. In contrast, here we demonstrate templated nucleic acid synthesis using a base-filling approach in which individual bases are added to...

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Detalles Bibliográficos
Autores principales: Heemstra, Jennifer M., Liu, David R.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726731/
https://www.ncbi.nlm.nih.gov/pubmed/19722647
http://dx.doi.org/10.1021/ja904712t