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Lentiviral Vectors with Amplified Beta Cell-Specific Gene Expression
An important goal of gene therapy is to be able to deliver genes so that they express in a pattern that recapitulates the expression of an endogenous cellular gene. Although tissue-specific promoters confer selectivity, in a vector-based system, their activity may be too weak to mediate detectable l...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726899/ https://www.ncbi.nlm.nih.gov/pubmed/19440227 http://dx.doi.org/10.1038/gt.2009.49 |