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Effect of casopitant, a novel NK-1 antagonist, on the pharmacokinetics of dolasetron and granisetron

OBJECTIVE: The objective of this study was to characterize the impact of casopitant, a novel neurokinin-1 receptor antagonist under investigation for the prevention of postoperative and chemotherapy-induced nausea and vomiting, on the pharmacokinetics of the commonly prescribed 5-hydroxytryptamine r...

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Detalles Bibliográficos
Autores principales: Adams, Laurel M., Johnson, Brendan, Zhang, Ke, Yue, Lin, Kirby, Lyndon C., Lebowitz, Peter, Stoltz, Randall
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726911/
https://www.ncbi.nlm.nih.gov/pubmed/19205754
http://dx.doi.org/10.1007/s00520-008-0572-4