Stable generation of serum- and feeder-free embryonic stem cell-derived mice with full germline-competency by using a GSK3 specific inhibitor

C57BL/6 (B6)-derived embryonic stem (ES) cells are not widely used to generate knockout mice despite the advantage of a well-defined genetic background because of poor developmental potential. We newly established serum- and feeder-free B6 ES cells with full developmental potential by using leukemia...

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Detalles Bibliográficos
Autores principales: Sato, Hiromu, Amagai, Keiko, Shimizukawa, Rie, Tamai, Yoshitaka
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726955/
https://www.ncbi.nlm.nih.gov/pubmed/19391115
http://dx.doi.org/10.1002/dvg.20514

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