Models for Prediction of Factor VIII Half-Life in Severe Haemophiliacs: Distinct Approaches for Blood Group O and Non-O Patients

BACKGROUND: Von Willebrand factor (VWF) is critical for the in vivo survival of factor VIII (FVIII). Since FVIII half-life correlates with VWF-antigen pre-infusion levels, we hypothesized that VWF levels are useful to predict FVIII half-life. METHODOLOGY: Standardized half-life studies and analysis...

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Detalles Bibliográficos
Autores principales: Fischer, Kathelijn, Pendu, Ronan, van Schooten, Carina J., van Dijk, Karin, Denis, Cécile V., van den Berg, H. Marijke, Lenting, Peter J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727052/
https://www.ncbi.nlm.nih.gov/pubmed/19707594
http://dx.doi.org/10.1371/journal.pone.0006745

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