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Elongation Factor 1 alpha interacts with phospho-Akt in breast cancer cells and regulates their proliferation, survival and motility
BACKGROUND: Akt/PKB is a serine/threonine kinase that has attracted much attention because of its central role in regulating cell proliferation, survival, motility and angiogenesis. Activation of Akt in breast cancer portends aggressive tumour behaviour, resistance to hormone-, chemo-, and radiother...
Autores principales: | Pecorari, Luisa, Marin, Oriano, Silvestri, Chiara, Candini, Olivia, Rossi, Elena, Guerzoni, Clara, Cattelani, Sara, Mariani, Samanta A, Corradini, Francesca, Ferrari-Amorotti, Giovanna, Cortesi, Laura, Bussolari, Rita, Raschellà, Giuseppe, Federico, Massimo R, Calabretta, Bruno |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727493/ https://www.ncbi.nlm.nih.gov/pubmed/19646290 http://dx.doi.org/10.1186/1476-4598-8-58 |
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