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Mechanism of PP2A-mediated IKKβ dephosphorylation: a systems biological approach
BACKGROUND: Biological effects of nuclear factor-κB (NFκB) can differ tremendously depending on the cellular context. For example, NFκB induced by interleukin-1 (IL-1) is converted from an inhibitor of death receptor induced apoptosis into a promoter of ultraviolet-B radiation (UVB)-induced apoptosi...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727496/ https://www.ncbi.nlm.nih.gov/pubmed/19607706 http://dx.doi.org/10.1186/1752-0509-3-71 |