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Dopamine modulates an intrinsic mGluR5-mediated depolarization underlying prefrontal persistent activity
Intrinsic properties of neurons that enable them to maintain depolarized, persistently activated states in the absence of sustained input are poorly understood. In short-term memory tasks, individual prefrontal cortical (PFC) neurons are capable of maintaining persistent action potential output duri...
Autores principales: | Sidiropoulou, Kyriaki, Lu, Fang-Min, Fowler, Melissa A., Xiao, Rui, Phillips, Christopher, Ozkan, Emin D., Zhu, Michael X., White, Francis J., Cooper, Donald C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727588/ https://www.ncbi.nlm.nih.gov/pubmed/19169252 http://dx.doi.org/10.1038/nn.2245 |
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