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Equilibrium and Kinetic Investigations of the Interaction of Model Platinum(II) Complex with DNA Constituents in Reference to the Antitumour Activity: Complex-Formation Reactions of [Pd(N,N-diethylethylenediamine)(H(2)O)(2)](2+) with Ligands of Biological Significance and Displacement Reactions of DNA Constituents
The [Pd(DEEN)Cl(2)] and [Pt(DEEN)Cl(2)] complexes were synthesized and characterized where DEEN = N,N-diethylethylenediamine. The stoichiometry and stability of the complexes formed between various biologically relevant ligands (amino acids, peptides, DNA constituents and dicarboxylic acids) and [Pd...
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| Formato: | Texto |
| Lenguaje: | English |
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Hindawi Publishing Corporation
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727661/ https://www.ncbi.nlm.nih.gov/pubmed/19696935 http://dx.doi.org/10.1155/2009/512938 |