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Severe hypoxia induces chemo-resistance in clinical cervical tumors through MVP over-expression
Oxygen molecule modulates tumour response to radiotherapy. Higher radiation doses are required under hypoxic conditions to induce cell death. Hypoxia may inhibit the non-homologous end-joining DNA repair through down regulating Ku70/80 expression. Hypoxia induces drug resistance in clinical tumours,...
Autores principales: | Lara, Pedro C, Lloret, Marta, Clavo, Bernardino, Apolinario, Rosa M, Henríquez-Hernández, Luis Alberto, Bordón, Elisa, Fontes, Fausto, Rey, Agustín |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728103/ https://www.ncbi.nlm.nih.gov/pubmed/19660100 http://dx.doi.org/10.1186/1748-717X-4-29 |
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