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Bub1 and Bub3 promote the conversion from monopolar to bipolar chromosome attachment independently of shugoshin
The eukaryotic spindle assembly checkpoint (SAC) delays anaphase in the presence of chromosome attachment errors. Bub3 has been reported to be required for SAC activity in all eukaryotes examined so far. We find that Bub3, unlike its binding partner Bub1, is not essential for the SAC in fission yeas...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728212/ https://www.ncbi.nlm.nih.gov/pubmed/19680287 http://dx.doi.org/10.1038/embor.2009.183 |