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FG/FxFG as well as GLFG repeats form a selective permeability barrier with self-healing properties
The permeability barrier of nuclear pore complexes (NPCs) controls all nucleo-cytoplasmic exchange. It is freely permeable for small molecules. Objects larger than ≈30 kDa can efficiently cross this barrier only when bound to nuclear transport receptors (NTRs) that confer translocation-promoting pro...
Autores principales: | Frey, Steffen, Görlich, Dirk |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728434/ https://www.ncbi.nlm.nih.gov/pubmed/19680227 http://dx.doi.org/10.1038/emboj.2009.199 |
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