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Probe-level estimation improves the detection of differential splicing in Affymetrix exon array studies

The recent advent of exon microarrays has made it possible to reveal differences in alternative splicing events on a global scale. We introduce a novel statistical procedure that takes full advantage of the probe-level information on Affymetrix exon arrays when detecting differential splicing betwee...

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Detalles Bibliográficos
Autores principales: Laajala, Essi, Aittokallio, Tero, Lahesmaa, Riitta, Elo, Laura L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728531/
https://www.ncbi.nlm.nih.gov/pubmed/19607685
http://dx.doi.org/10.1186/gb-2009-10-7-r77