Functional Dynamics of the Folded Ankyrin Repeats of IκBα Revealed by Nuclear Magnetic Resonance

[Image: see text] Inhibition of nuclear factor κB (NF-κB) is mainly accomplished by IκBα, which consists of a signal response sequence at the N-terminus, a six-ankyrin repeat domain (ARD) that binds NF-κB, and a C-terminal PEST sequence. Previous studies with the ARD revealed that the fifth and sixt...

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Detalles Bibliográficos
Autores principales: Cervantes, Carla F., Markwick, Phineus R. L., Sue, Shih-Che, McCammon, J. Andrew, Dyson, H. Jane, Komives, Elizabeth A.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728578/
https://www.ncbi.nlm.nih.gov/pubmed/19591507
http://dx.doi.org/10.1021/bi900712r

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728578/
https://www.ncbi.nlm.nih.gov/pubmed/19591507
http://dx.doi.org/10.1021/bi900712r

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