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Nucleic acid polymerases employ a general acid for nucleotidyl transfer

Nucleic acid polymerases catalyze the formation of DNA or RNA from nucleoside-triphosphate precursors. Amino acid residues in the active site of polymerases are thought to contribute only indirectly to catalysis by serving as ligands for the two divalent cations required for activity or substrate bi...

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Detalles Bibliográficos
Autores principales: Castro, Christian, Smidansky, Eric D., Arnold, Jamie J., Maksimchuk, Kenneth R., Moustafa, Ibrahim, Uchida, Akira, Götte, Matthias, Konigsberg, William, Cameron, Craig E.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728625/
https://www.ncbi.nlm.nih.gov/pubmed/19151724
http://dx.doi.org/10.1038/nsmb.1540

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