Structural and functional implications of the complement convertase stabilized by a staphylococcal inhibitor

Activation of the complement system generates potent chemoattractants and opsonizes cells for immune clearance. Short-lived protease complexes cleave complement component C3 into anaphylatoxin C3a and opsonin C3b. Here we report the crystal structure of the C3 convertase formed by C3b and the protea...

Descripción completa

Detalles Bibliográficos
Autores principales: Rooijakkers, Suzan H M, Wu, Jin, Ruyken, Maartje, van Domselaar, Robert, Planken, Karel L, Tzekou, Apostolia, Ricklin, Daniel, Lambris, John D, Janssen, Bert J C, van Strijp, Jos A G, Gros, Piet
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729104/
https://www.ncbi.nlm.nih.gov/pubmed/19503103
http://dx.doi.org/10.1038/ni.1756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729104/
https://www.ncbi.nlm.nih.gov/pubmed/19503103
http://dx.doi.org/10.1038/ni.1756

Ejemplares similares