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Comparative Analysis of Gene Regulation by the Transcription Factor PPARα between Mouse and Human

BACKGROUND: Studies in mice have shown that PPARα is an important regulator of hepatic lipid metabolism and the acute phase response. However, little information is available on the role of PPARα in human liver. Here we set out to compare the function of PPARα in mouse and human hepatocytes via anal...

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Detalles Bibliográficos
Autores principales: Rakhshandehroo, Maryam, Hooiveld, Guido, Müller, Michael, Kersten, Sander
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729378/
https://www.ncbi.nlm.nih.gov/pubmed/19710929
http://dx.doi.org/10.1371/journal.pone.0006796