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Primary Cilia Are Not Required for Normal Canonical Wnt Signaling in the Mouse Embryo
BACKGROUND: Sonic hedgehog (Shh) signaling in the mouse requires the microtubule-based organelle, the primary cilium. The primary cilium is assembled and maintained through the process of intraflagellar transport (IFT) and the response to Shh is blocked in mouse mutants that lack proteins required f...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729396/ https://www.ncbi.nlm.nih.gov/pubmed/19718259 http://dx.doi.org/10.1371/journal.pone.0006839 |