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Epistatic Roles of E2 Glycoprotein Mutations in Adaption of Chikungunya Virus to Aedes Albopictus and Ae. Aegypti Mosquitoes
Between 2005 and 2007 Chikungunya virus (CHIKV) caused its largest outbreak/epidemic in documented history. An unusual feature of this epidemic is the involvement of Ae. albopictus as a principal vector. Previously we have demonstrated that a single mutation E1-A226V significantly changed the abilit...
Autores principales: | Tsetsarkin, Konstantin A., McGee, Charles E., Volk, Sara M., Vanlandingham, Dana L., Weaver, Scott C., Higgs, Stephen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729410/ https://www.ncbi.nlm.nih.gov/pubmed/19718263 http://dx.doi.org/10.1371/journal.pone.0006835 |
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