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Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death
Purkinje cells are a class of specialized neurons in the cerebellum, and are among the most metabolically active of all neurons, as they receive immense synaptic stimulation, and provide the only efferent output from the cerebellum. Degeneration of Purkinje cells is a common feature of inherited ata...
Autores principales: | Chakrabarti, Lisa, Eng, Jeremiah, Ivanov, Nishi, Garden, Gwenn A, La Spada, Albert R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729476/ https://www.ncbi.nlm.nih.gov/pubmed/19640278 http://dx.doi.org/10.1186/1756-6606-2-24 |
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