Human Embryonic Stem Cell Differentiation Toward Regional Specific Neural Precursors

Human embryonic stem cells (hESCs) are self-renewing pluripotent cells that have the capacity to differentiate into a wide variety of cell types. This potentiality represents a promising source to overcome many human diseases by providing an unlimited supply of all cell types, including cells with n...

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Detalles Bibliográficos
Autores principales: Erceg, Slaven, Ronaghi, Mohammad, Stojković, Miodrag
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2009
Materias:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729673/
https://www.ncbi.nlm.nih.gov/pubmed/18845761
http://dx.doi.org/10.1634/stemcells.2008-0543
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author Erceg, Slaven
Ronaghi, Mohammad
Stojković, Miodrag
author_facet Erceg, Slaven
Ronaghi, Mohammad
Stojković, Miodrag
author_sort Erceg, Slaven
collection PubMed
description Human embryonic stem cells (hESCs) are self-renewing pluripotent cells that have the capacity to differentiate into a wide variety of cell types. This potentiality represents a promising source to overcome many human diseases by providing an unlimited supply of all cell types, including cells with neural characteristics. Therefore, this review summarizes early neural development and the potential of hESCs to differentiate under in vitro conditions, examining at the same time the potential use of differentiated hESCs for therapeutic applications for neural tissue and cell regeneration.
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spelling pubmed-27296732009-08-27 Human Embryonic Stem Cell Differentiation Toward Regional Specific Neural Precursors Erceg, Slaven Ronaghi, Mohammad Stojković, Miodrag Stem Cells Embryonic Stem Cells/Induced Pluripotent Stem Cells Human embryonic stem cells (hESCs) are self-renewing pluripotent cells that have the capacity to differentiate into a wide variety of cell types. This potentiality represents a promising source to overcome many human diseases by providing an unlimited supply of all cell types, including cells with neural characteristics. Therefore, this review summarizes early neural development and the potential of hESCs to differentiate under in vitro conditions, examining at the same time the potential use of differentiated hESCs for therapeutic applications for neural tissue and cell regeneration. Wiley Subscription Services, Inc., A Wiley Company 2009-01 /pmc/articles/PMC2729673/ /pubmed/18845761 http://dx.doi.org/10.1634/stemcells.2008-0543 Text en Copyright © 2009 AlphaMed Press http://creativecommons.org/licenses/by/2.5/ Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.
spellingShingle Embryonic Stem Cells/Induced Pluripotent Stem Cells
Erceg, Slaven
Ronaghi, Mohammad
Stojković, Miodrag
Human Embryonic Stem Cell Differentiation Toward Regional Specific Neural Precursors
title Human Embryonic Stem Cell Differentiation Toward Regional Specific Neural Precursors
title_full Human Embryonic Stem Cell Differentiation Toward Regional Specific Neural Precursors
title_fullStr Human Embryonic Stem Cell Differentiation Toward Regional Specific Neural Precursors
title_full_unstemmed Human Embryonic Stem Cell Differentiation Toward Regional Specific Neural Precursors
title_short Human Embryonic Stem Cell Differentiation Toward Regional Specific Neural Precursors
title_sort human embryonic stem cell differentiation toward regional specific neural precursors
topic Embryonic Stem Cells/Induced Pluripotent Stem Cells
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729673/
https://www.ncbi.nlm.nih.gov/pubmed/18845761
http://dx.doi.org/10.1634/stemcells.2008-0543
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AT ronaghimohammad humanembryonicstemcelldifferentiationtowardregionalspecificneuralprecursors
AT stojkovicmiodrag humanembryonicstemcelldifferentiationtowardregionalspecificneuralprecursors

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