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Tumor Immunotherapy Using Gene-Modified Human Mesenchymal Stem Cells Loaded into Synthetic Extracellular Matrix Scaffolds
Mesenchymal stem cells (MSCs) are appealing as gene therapy cell vehicles given their ease of expansion and transduction. However, MSCs exhibit immunomodulatory and proangiogenic properties that may pose a risk in their use in anticancer therapy. For this reason, we looked for a strategy to confine...
Autores principales: | Compte, Marta, Cuesta, Ángel M, Sánchez-Martín, David, Alonso-Camino, Vanesa, Vicario, José Luís, Sanz, Laura, Álvarez-Vallina, Luís |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2729675/ https://www.ncbi.nlm.nih.gov/pubmed/19096041 http://dx.doi.org/10.1634/stemcells.2008-0831 |
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