Circadian Dysregulation Disrupts Bile Acid Homeostasis

BACKGROUND: Bile acids are potentially toxic compounds and their levels of hepatic production, uptake and export are tightly regulated by many inputs, including circadian rhythm. We tested the impact of disrupting the peripheral circadian clock on integral steps of bile acid homeostasis. METHODOLOGY...

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Detalles Bibliográficos
Autores principales: Ma, Ke, Xiao, Rui, Tseng, Hsiu-Ting, Shan, Lu, Fu, Loning, Moore, David D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730029/
https://www.ncbi.nlm.nih.gov/pubmed/19718444
http://dx.doi.org/10.1371/journal.pone.0006843

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